Vitamin E is safe: Vitamin E Makeover

Over the past couple of years, a handful of ridiculously flawed studies have found vitamin E supplements to be ineffective and even (brace
yourself!) dangerous. The result: public perception of the vitamin has taken a beating.

Obviously its time for a makeover

Vitamin E: One bad study

Earlier this month, the American Oil Chemists Society (AOCS) annual meeting featured a symposium in which several prominent scientists defended the honour of vitamin E.

Its too bad that a nutrient with such a large body of evidence proving its usefulness would even need defending. But in the wake of recent media reports that highlight a couple of negative vitamin E studies and completely ignored the scores of positive studies, public perception of the vitamin is at an all-time low.

Most of vitamin Es image problem can be traced to one bad study: the now infamous Johns Hopkins research that appeared in the Annals of Internal Medicine about a year and a half ago. As noted at the AOCS symposium, the Hopkins team conducted a meta-analysis of 19 vitamin E studies and concluded that more than 400 IU per day may slightly increase the risk of death.

Which is absolutely preposterous.

Commenting on the study in an e-Alert at the time, HSI Panellist Dr Allan Spreen noted that the Hopkins conclusion flies in the face of decades of research, using doses up to 2,400 IU. And a representative for the US Council for Responsible Nutrition (CRN) added that it was inappropriate for the researchers to draw conclusions for the entire population based on studies of subjects who were already at grave risk with existing diseases including cancer, heart disease, Alzheimers, Parkinsons and kidney failure.

But never mind these glaring flaws the mainstream media certainly didnt mind them! The AOCS moderator, University of Arizona professor Ronald Watson, Ph.D., specifically cited poor journalism
as a key factor in discouraging consumers from taking advantage of this beneficial nutrient.

Vitamin E: Form and function

This cant be said often enough: When vitamin E is evaluated, the form of the vitamin is crucial. Too often weve seen vitamin E intervention studies (including some in the Hopkins research) that used a synthetic form or an inferior form of the vitamin.
Dr Spreen: No one should be taking the synthetic form of the nutrient (dl-alpha tocopherol) it should be d-alpha tocopherol at least. Even better is to take mixed tocopherols (alpha, beta, delta, gamma). Also, vitamin E functions better when its mixed with selenium.

Its SO SIMPLE! As with all vitamins, there are different forms. Use the wrong form and you get poor results. Use the proper form and you get good results.

Vitamin E: Back on track

Lets complete vitamin Es makeover by addressing an e-mail I recently received from an HSI member named
JL: Is there any truth to a recent article about anyone taking 50 IUs of vitamin E is at greater risk for a stroke?

JL didnt include specific information from the article, and I havent been able to pinpoint any studies with those results, so well have to assume that the study in question either: A) examined subjects already at risk of a stroke, and/or B) used an ineffective or synthetic form of the vitamin.

Of course, we should never assume, so lets go back a few years to a time when vitamin E still looked pretty spiffy.

In a 1993 Harvard study published in the New England Journal of Medicine, researchers examined eight years of medical records for more than 87,000 women between the ages of 34 and 59. At the outset of the study, none of the subjects had been diagnosed with either cardiovascular disease or cancer.

The results: Women who took vitamin E supplements (at least 100 IU daily) for two years or more reduced their heart disease risk by more than 40 per cent compared to women who didnt take E supplements. And in this same group, risk of ischaemic stroke was reduced by nearly 30 per cent.
In the lowest-risk group, the average intake was 200 IU per day.

Theres your makeover, Vitamin E. In spite of all the undeserved hits youve been taking, you look MAHvelous!

Sources:

Vitamin E Symposium Reacts to Negative Press
NutraIngredients USA, 5/12/06, nutraingredients- usa.com
Meta-Analysis: High-Dosage Vitamin E
Supplementation May Increase All-Cause Mortality
Annals of Internal Medicine, Vo. 142, No. 1, 1/4/05, annals.org Vitamin E Consumption and the Risk of Coronary Disease in Women New England Journal of Medicine, Vol. 328, No. 20, 5/20/93, content.nejm.org Stomach bug makes food yield more calories, www.nature.com, 5/26/06