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Cancer

Colorectal Polyps Could Be Reduced By Ingredient Found In Curry


Date: 31/08/06
 
A somewhat rare condition might lead researchers to a noninvasive cancer solution for people with a far more common condition: colorectal polyps. Researchers at Johns Hopkins University School of Medicine recently tested the effects of curcumin and quercetin (a plant flavanoid found in apples and onions) on five FAP patients...

A somewhat rare condition might lead researchers to a noninvasive cancer solution for people with a far more common condition: colorectal polyps.

Years in the making

Familial adenomatous polyposis (FAP) is a hereditary condition. FAP patients typically begin to develop numerous benign polyps in the colon when they're only in their teens.

Polyps continue to multiply into the hundreds and sometimes thousands as FAP patients age. Eventually the polyps become malignant, usually when patients reach their 50s. Before malignancy, polyps can be removed during colonoscopy, although this may not be practical with patients who have very high polyp counts. Once malignancy begins, the colon has to be removed.

Nonsteroidal anti-inflammatory drugs and COX-2 inhibitors can sometimes reverse the progression of polyps, but as I've noted in many e-Alerts, these drugs commonly produce harsh adverse side effects when taken on a regular basis.

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