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Ageing

L-carnitine: Maximize Your Chances Of Living A Long And Healthy Life


Date: 31/01/08
 
Keywords: Ageing, L-arginine
Will you still need me, will you still feed me, when I'm 104? You may recognize that question as a slight rewording (or rather, renumbering) from the Beatles song 'When I'm 64.' The original lyric, written by Paul McCartney, was recorded when he was 24, four decades shy of 64. When Paul turned 64, I wonder if he looked ahead another four decades and pondered what life might be like at 104. Safe to say, most of us don't expect to celebrate many birthdays beyond ten decades. But when researchers recently conducted a trial restricted to subjects over the age of 100, they found surprising results that are enlightening for Paul and anyone else who's interested in maintaining good health into advanced age.

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Will you still need me, will you still feed me, when I'm 104? 
 
You may recognize that question as a slight rewording (or rather, renumbering) from the Beatles song 'When I'm 64.' 
 
The original lyric, written by Paul McCartney, was recorded when he was 24, four decades shy of 64. When Paul turned 64, I wonder if he looked ahead another four decades and pondered what life might be like at 104. 
 
Safe to say, most of us don't expect to celebrate many birthdays beyond ten decades. But when researchers recently conducted a trial restricted to subjects over the age of 100, they found surprising results that are enlightening for Paul and anyone else who's interested in maintaining good health into advanced age.  
 
L-carnitine: Doing the garden, digging the weeds  
 
In addition to the question 'Will you still feed me?' we might also ask, 'What will you feed me?' 
 
If the answer includes plenty of meat, chicken, fish, and dairy products, then the body will be getting the raw materials it needs to increase levels of L-carnitine, a key amino acid.  
 
L-carnitine is responsible for a number of important functions:

* Delivers omega-3 fatty acids to cell mitochondria
* Helps protect cells from damage � especially heart cells
* Raises the levels of enzymes needed to metabolize carbohydrates
* Helps boost cellular energy
* Helps maintain muscle strength

But there are two problems associated with L-carnitine:
1) The body only absorbs about a quarter of the L-carnitine supplied by food, and
2) The body produces less L-carnitine as we age. 
 
Over the long term, that ageing attrition creates predictable results.  
 

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L-carnitine: You'll be older too
  

In an issue of the American Journal of Clinical Nutrition, researchers at the University of Catania in Italy reported on a study in which they examined the effects of L-carnitine supplementation on 66 subjects. And as I mentioned above, each subject were at least 100 years old. In addition, all the subjects experienced fatigue after slight physical activity. 
 
Subjects were divided into two groups to receive either two grams of L-carnitine daily or a placebo for six months. 
 
At the end of the intervention, tests revealed five remarkable results:

* Physical fatigue after exercise was significantly less in the L-carnitine group
* Mental fatigue was significantly less in the L-carnitine group
* In a 30-point test to assess cognitive sharpness, subjects in the L-carnitine group scored more than four points higher on average than subjects in the placebo group
* Total muscle mass was significantly higher in the L-carnitine group
* Total fat mass was significantly lower in the L-carnitine group Elderly people are not the only ones who might benefit from L-carnitine supplementation.  
 
A study examined the effects of several different dosage levels of L-carnitine on cancer patients who experienced moderate to severe fatigue. Overall, fatigue and depression decreased considerably in subjects who took L-carnitine, while sleep problems were also alleviated. The most pronounced results were found among subjects who received the highest doses  3grams per day. Even at these higher doses, the supplements were well tolerated. 
 
Talk to your doctor before supplementing with L-carnitine. 

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