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Arthritis

Arthritis: The Harmful Arthritis Drug That's Banned In The US But Not In The UK


Date: 02/07/07
 
Keywords: Arthritis,
It looks like the US Food and Drug Administration (FDA) has actually made a sound decision for once one based on the best interests of human health and safety and not on its own back pocket. It rejected Merck's proposed replacement for its now-disgraced arthritis darling Vioxx.

Surgeon's Knife
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I know I'm always telling you not to believe everything you read, and if I hadn't read it from numerous sources (ones I've come to respect and trust) I wouldn't believe it myself.

But it looks like the US Food and Drug Administration (FDA) has actually made a sound decision for once one based on the best interests of human health and safety and not on its own back pocket. It rejected Merck's proposed replacement for its now-disgraced arthritis darling Vioxx.
Of course, the new drug, Arcoxia, would probably be on the market right now if the whole Vioxx scandal hadn't erupted a few years ago. Arcoxia was already on the FDA's waiting-for-approval list when Vioxx was linked to increased risk of heart attack and stroke.

Since Arcoxia is in the same drug class as Vioxx, the FDA decided to try and save a little face by insisting the Merck provide further safety and efficacy information on the new drug before it would consider approving it.
Apparently, what Merck came back with must have been really unconvincing for the FDA to still give it the axe.  br>Unfortunately Arcoxia is available in over 60 other countries, including the UK, and Merck is determined to add the US to that list, saying that they're 'committed to working with the FDA to determine the best approach to get it on the US market.

Its list of side effects
Arcoxia is linked to:

* Headache
* Dizziness
* Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting, indigestion, flatulence or abdominal pain
* Excessive fluid retention in the body tissues, resulting in swelling
(oedema)
* High blood pressure (hypertension)
* Weakness or loss of strength (asthenia)
* Fatigue
* Cold or flu-like symptoms
* Skin reactions such as rash and itch
* Blurred vision
* Difficulty in sleeping (insomnia)
* Muscle cramps
* Weight gain
* Anxiety
* Depression
* Nosebleeds (epistaxis)
* Shortness of breath (dyspnoea)
* Chest pain
* Heart attack or stroke
* Ulceration or bleeding of the stomach or intestine
* Liver or kidney disorders

Makes for extremely worrying reading I'm sure youll agree!

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Comments

John Atkins Posted 26/05/2008

Since taking Arcoxia I have experienced indigestion problems and also blood in stools and a feel of bloating. It has helped to a degree the pain in my joints but I am anxious to continue with treatment as I suffer from high blood pressure and I am on various other medications.Please advise. Many thanks

Fred Posted 18/11/2008

Most drugs are 'linked' to quite severe adverse effects. While adverse reactions to Vioxx were associated with long-term high dosage use. The likelihood of adverse side-effects actually happening are possible but rare, especially in healthy individuals with minimal (or no) risk factors. Problems are more likely to occur in patients naturally predisposed to one (or more) of the above-mentioned problems.



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