Arthritis: After Vioxx Drug Scare Kaprex Offers A Safe Way To Beat Arthritis

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Weve covered natural arthritis remedies many times over the years. And now that Vioxx, the pharmaceutical drug many people relied on for pain relief, has been pulled from the market, we thought it was the perfect time to report on the latest all-natural and safe arthritis remedy that has just become available in the UK Kaprex.

Arthritis: Vioxx pulled after trial showed it increased the risk of heart attacks and strokes
In case youre not familiar with the Vioxx situation, heres a recap: Vioxxs manufacturer, Merck, recently launched a large, randomised trial of 2,600 patients with colon polyps in the hope of proving that Vioxx could be used to help their condition.

In the process, though, Merck discovered that 3.5 per cent of the patients taking Vioxx suffered heart attacks or strokes versus 1.9 per cent taking a placebo. Based on this finding, Merck withdrew the drug from the market altogether.

This must have come as a devastating blow to those people who depended on Vioxx for arthritis relief. But the good news is youre not limited anymore to treatments like Vioxx that just mask pain or put you at risk of unrelated, more serious problems. Kaprex doesnt trick your body by blocking pain receptors it actually stops the cause of the damage to the joint.

Arthritis: Block your bodys damage-causing signals
Kaprex works by interfering with signals in the body that result in the production of damaging compounds that negatively impact cartilage and other joint tissues and cause your pain.

To find the best candidates for the formula, product developers at Metagenics MetaProteomics Research Centre in the US screened over 150 natural substances. These laboratory tests examined each potential ingredient for efficacy by studying its effect on cell protein synthesis and activity. The researchers compiled and analysed thousands of research data and selected three natural ingredients based on their outstanding effectiveness and performance scores hops, oleanolic acid and rosemary.

Recent research suggests that components of hops such as reduced isoalpha acids may inhibit the formation of inflammation-causing prostaglandins.1 The form added to Kaprex is a proprietary extract of hops called Luduxin.

Oleanolic acid is derived from olive leaf extract. Research indicates that it may support joint health as a pain reliever as well as protect against potential damage to your stomach lining.

And rosemary leaf extract stimulates circulation and eases pain by increasing your blood supply.

Although these herbs were chosen for their individual arthritis-relieving properties, the product developers found that when they put all of them together the effects were even better. Think of it as herbal teamwork.

Arthritis: Pain relief that doesnt compromise the integrity of your gastrointestinal tract
According to Dr Joseph Debe, a chiropractor and board certified nutritionist, one of the things that sets Kaprex apart from other arthritis remedies, including over-the-counter pain relievers, is that it doesnt appear to cause stomach damage or irritation.

Researchers have found that Kaprex has minimal GI [gastrointestinal] cell activity and therefore a high level of predicted GI safety. Both non-steroidal anti-inflammatory drugs and Kaprex work by reducing the concentration of a body chemical called prostaglandin E2 (PGE2), but they do so through different mechanisms.

PGE2 is a powerful hormone-like chemical that is responsible for producing the majority of the inflammation and pain associated with arthritis and other conditions.

Another impact of accumulated PGE2 is heightened sensitivity in your nerve fibres where even the slightest movement can cause inordinate pain. It takes a while for it to build up, so at first you may just be a little stiff and sore. But the symptoms increase progressively until any joint movement becomes extremely painful.

Arthritis: Kaprex gets to work quickly to provide relief from joint pain
The conventional non-steroidal anti-inflammatory drugs reduce levels of PGE2 by inhibiting the activity of the enzymes that manufacture it. But, unfortunately, not only is PGE2 production reduced in joints, it is also reduced in gastrointestinal tissues. And a certain level of PGE2 is necessary to keep gastrointestinal tissues healthy.

When PGE2 is deficient, it can contribute to ulcer formation. On the other hand, Kaprex works through a safer, upstream mechanism. It reduces the excessive formation of the PGE2-producing enzymes, rather than inhibiting their activity. It appears to actually reduce the message sent to the genes to manufacture the enzyme.

This makes all the difference in terms of gastrointestinal injury developing. The net effect is that Kaprex is active in joint tissues without affecting the gastrointestinal tract.

A recent study examined Kaprexs absorbability and bioavailability. Six subjects supplemented on different days with either: one Kaprex tablet, three Kaprex tablets, or one Celebrex (a non-steroidal anti-inflammatory drug) capsule. Their blood was drawn prior to dosing and at one, two, four, six, and eight hours after dosing. The blood samples were analysed for their ability to reduce PGE2 levels.

Kaprex worked quickly and maintained effectiveness for hours, with activity beginning to decrease after eight hours. One tablet of Kaprex appeared to be as effective as one capsule of Celebrex and worked more rapidly. As you might expect, three tablets of Kaprex produced a significantly greater effect than just one tablet.2

Arthritis: What to take for best results
The recommended dosage for Kaprex is one tablet taken three times a day.
Arthritis - Realted Reading:
How to alleviate pain caused by osteoarthritis of the knee

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Natural Pain Relief: The Herbs That Can Put A Stop To Chronic Pain

1. Babish JG, Howell T. Proprietary Research Report. San Clemente, CA: MetaProteomics, Inc. 2003. and Yamamoto K, Wang J, Yamamoto S, et al. Suppression of cyclooxygenase-2 gene transcription by humulon of beer hop extract studied with reference to glucocorticoid. FEBS Lett 2000;465:103-06.
2. http://www.newliving.com/issues/oct_2003/articles/newnatural.html