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Cancer
Studies Reveal CoQ10’s Cancer-Fighting Potential
Date: 14/10/10
Regular readers of the Daily Health will know that we’ve written on numerous occasions about the heart benefits of Coenzyme Q10 (CoQ10) — the vitamin-like substance found in every cell of the human body. In fact, many regard CoQ10 to be a heart-critical nutrient, especially for those taking cholesterol lowering statins.
CoQ10’s health claims also include the prevention of nerve damage, brain cell deterioration, abnormal cell growth, breathing problems, gum infections, muscle wasting, blood sugar imbalance, skin damage, headaches, obesity and infertility.
But very few people know that CoQ10 is also showing enormous potential in the fight against cancer... Numerous small clinical studies have proven this, but as always, the medical mainstream is turning a blind eye...
Massive potential kept under wraps
In 1961 when CoQ10 deficiency was detected in patients with breast and other forms of cancer, it sparked an interest in this nutrient as a possible preventative and treatment for cancer. As a result, a subsequent study showed a statistically significant relationship between the degree of CoQ10 deficiency and the progression of breast cancer.
As expected, these encouraging findings on a potentially successful approach to cancer management have been overlooked and ‘conveniently’ forgotten over the years.
Early research was carried out by Dr Karl Folkers, a biochemist and director of the Institute for Biomedical Research at the University of Texas, in the US, who became interested in CoQ10 when his next-door neighbour who had terminal metastatic lung cancer, started taking CoQ1O and experienced a complete remission from the disease.
In 1993, Dr. Folkers, arranged for the first clinical trial of CoQ10 to be carried out in Copenhagen, Denmark.
Doctors treated 32 patients with advanced, "high risk" breast cancer. In addition to conventional treatment, each patient was given 90mg of CoQ10 per day. They also received other vitamins, minerals, antioxidants, and essential fatty acids.
On this regimen, 6 (18.8 per cent) of the 32 patients showed partial tumour regressions — which is significant in advanced cancer patients.
Then in October 1993, a strange thing happened: one of these six women, on her own, increased her dosage of CoQ10 from 90 to 390mg per day. A month later, her doctors wrote, "the tumour was no longer palpable and in the following month, a mammogram confirmed the disappearance of her tumour. After that, another woman in the group also increased her dose, this time to 300mg. Her tumour also soon disappeared and a clinical examination revealed no evidence of the prior residual tumour, nor of distant metastases."
Now, we all know that what you’ve just read is bordering on being anecdotal and would never stand on its own as hard scientific evidence, but still, it happened...
One of the researchers participating in this study said that he had seen around 200 cases of breast cancer a year, but he had "never seen a spontaneous complete regression of 1.5-to 2.0cm tumour, and had never seen a comparable regression following any conventional anti-tumour therapy in his 35 years of oncology practice."
Let’s not forget that those impressive results were achieved on very low dosage amounts (90mg). The patients made the greatest discoveries!
A further study published in the journal Clinical Biochemistry, in 2000, analysed the relationship between oxidative stress and breast cancer development and concluded that CoQ10 may offer protection against increased oxidative stress and its effects on breast tissue.
Another study including 80 breast cancer patients, found blood levels of CoQ10 were significantly lower, and this reduction was more pronounced in patients with larger tumour volume. Similar results have been reported in 116 patients with myeloma and breast cancer.
Falling on deaf ears
Unfortunately, the clinical data available (no matter how positive) on the use of treating and preventing cancer with CoQ10 doesn’t carry enough weight to convince the medical mainstream that we may be on to something very powerful here.
Big Pharma continues to have a negative attitude, despite convincing evidence, and shows a lack of interest in developing products based on coenzyme Q10. The obvious reason being that there is no patent protection on natural substances which limits its profit making potential.
While CoQ10 may have to wait a while before the medical mainstream acknowledge it as the spark of life it really is, they can’t argue with its excellent safety profile. No significant side effects have been observed in clinical studies involving thousands of patients on long-term high- dose CoQ10 treatment, other than mild gastro-intestinal symptoms in very rare cases.
It’s important to point out that while CoQ10 boasts some impressive health benefits, in order to get the most from your CoQ10 supplement make sure you’re taking it in its most active form — Ubiquinol. For more information, click here:
CoQ10 Realted Reading:
Green Tea And CoQ10 May Protect Against Gum And Heart Disease
Co-enzyme Q10 For a Healthy Heart
HOT TOPICS:
Prelox - New Erectile Dysfunction Treatment To Enhance Sex Life
Green Tea May Protect Against Breast Cancer
Prevent Arthritis and Promote Healthy Joints With Omega-3 Fatty Acids
Sources:
Coenzyme Q10 / Co Q10 / Stockholm Protocol, published online, cancertutor.com/Cancer/Q10.html
Coenzyme Q10 and Neoplasia: Overview of Experimental and Clinical Evidence, published online, coq10.co.nz
Clin. Biochem., 33, 279, 2000
Lockwood, K., Moesgaard, S., Hanioka, T., and Folkers, K., Apparent partial remission of breast cancer in “high risk” patients supplemented with nutritional antioxidants, essential fatty acids and coenzyme Q10, Mol. Aspects Med., 15, S231, 1994.
Lockwood, K., Moesgaard. S., and Folkers, K., Partial and complete regression of breast cancer in patients in relation to dosage of coenzyme Q10, Biochem. Biophys. Res. Commun., 199, 1504, 1994.
Back to topCoQ10’s health claims also include the prevention of nerve damage, brain cell deterioration, abnormal cell growth, breathing problems, gum infections, muscle wasting, blood sugar imbalance, skin damage, headaches, obesity and infertility.
But very few people know that CoQ10 is also showing enormous potential in the fight against cancer... Numerous small clinical studies have proven this, but as always, the medical mainstream is turning a blind eye...
Massive potential kept under wraps
In 1961 when CoQ10 deficiency was detected in patients with breast and other forms of cancer, it sparked an interest in this nutrient as a possible preventative and treatment for cancer. As a result, a subsequent study showed a statistically significant relationship between the degree of CoQ10 deficiency and the progression of breast cancer.
As expected, these encouraging findings on a potentially successful approach to cancer management have been overlooked and ‘conveniently’ forgotten over the years.
Early research was carried out by Dr Karl Folkers, a biochemist and director of the Institute for Biomedical Research at the University of Texas, in the US, who became interested in CoQ10 when his next-door neighbour who had terminal metastatic lung cancer, started taking CoQ1O and experienced a complete remission from the disease.
In 1993, Dr. Folkers, arranged for the first clinical trial of CoQ10 to be carried out in Copenhagen, Denmark.
Doctors treated 32 patients with advanced, "high risk" breast cancer. In addition to conventional treatment, each patient was given 90mg of CoQ10 per day. They also received other vitamins, minerals, antioxidants, and essential fatty acids.
On this regimen, 6 (18.8 per cent) of the 32 patients showed partial tumour regressions — which is significant in advanced cancer patients.
Then in October 1993, a strange thing happened: one of these six women, on her own, increased her dosage of CoQ10 from 90 to 390mg per day. A month later, her doctors wrote, "the tumour was no longer palpable and in the following month, a mammogram confirmed the disappearance of her tumour. After that, another woman in the group also increased her dose, this time to 300mg. Her tumour also soon disappeared and a clinical examination revealed no evidence of the prior residual tumour, nor of distant metastases."
Now, we all know that what you’ve just read is bordering on being anecdotal and would never stand on its own as hard scientific evidence, but still, it happened...
One of the researchers participating in this study said that he had seen around 200 cases of breast cancer a year, but he had "never seen a spontaneous complete regression of 1.5-to 2.0cm tumour, and had never seen a comparable regression following any conventional anti-tumour therapy in his 35 years of oncology practice."
Let’s not forget that those impressive results were achieved on very low dosage amounts (90mg). The patients made the greatest discoveries!
A further study published in the journal Clinical Biochemistry, in 2000, analysed the relationship between oxidative stress and breast cancer development and concluded that CoQ10 may offer protection against increased oxidative stress and its effects on breast tissue.
Another study including 80 breast cancer patients, found blood levels of CoQ10 were significantly lower, and this reduction was more pronounced in patients with larger tumour volume. Similar results have been reported in 116 patients with myeloma and breast cancer.
Falling on deaf ears
Unfortunately, the clinical data available (no matter how positive) on the use of treating and preventing cancer with CoQ10 doesn’t carry enough weight to convince the medical mainstream that we may be on to something very powerful here.
Big Pharma continues to have a negative attitude, despite convincing evidence, and shows a lack of interest in developing products based on coenzyme Q10. The obvious reason being that there is no patent protection on natural substances which limits its profit making potential.
While CoQ10 may have to wait a while before the medical mainstream acknowledge it as the spark of life it really is, they can’t argue with its excellent safety profile. No significant side effects have been observed in clinical studies involving thousands of patients on long-term high- dose CoQ10 treatment, other than mild gastro-intestinal symptoms in very rare cases.
It’s important to point out that while CoQ10 boasts some impressive health benefits, in order to get the most from your CoQ10 supplement make sure you’re taking it in its most active form — Ubiquinol. For more information, click here:
CoQ10 Realted Reading:
The Best Way to Administer CoQ10
Green Tea And CoQ10 May Protect Against Gum And Heart Disease
Co-enzyme Q10 For a Healthy Heart
HOT TOPICS:
Prelox - New Erectile Dysfunction Treatment To Enhance Sex Life
Green Tea May Protect Against Breast Cancer
Prevent Arthritis and Promote Healthy Joints With Omega-3 Fatty Acids
Sources:
Coenzyme Q10 / Co Q10 / Stockholm Protocol, published online, cancertutor.com/Cancer/Q10.html
Coenzyme Q10 and Neoplasia: Overview of Experimental and Clinical Evidence, published online, coq10.co.nz
Clin. Biochem., 33, 279, 2000
Lockwood, K., Moesgaard, S., Hanioka, T., and Folkers, K., Apparent partial remission of breast cancer in “high risk” patients supplemented with nutritional antioxidants, essential fatty acids and coenzyme Q10, Mol. Aspects Med., 15, S231, 1994.
Lockwood, K., Moesgaard. S., and Folkers, K., Partial and complete regression of breast cancer in patients in relation to dosage of coenzyme Q10, Biochem. Biophys. Res. Commun., 199, 1504, 1994.
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