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Cancer

Vitamin B6 Reduces The Risk of Colorectal Cancer


Date: 23/01/12
 
A recent study that linked aspirin with a reduced risk of colorectal cancer. First — the study only included patients with Lynch syndrome, a condition that sharply increases colorectal cancer risk. So while aspirin may have protected some Lynch syndrome patients from colorectal cancer, those results can't be extrapolated to the general population. Second — subjects in the study received 600mg of aspirin daily. And that's a long LONG way from the 81mg low dose that's commonly recommended for heart benefits. Those extra 519mg per day would dramatically increase risk of stomach bleeding, heart attack, and stroke — three known side effects caused by regular use of non-steroidal anti- inflammatory drugs (NSAIDs), which includes aspirin. So let's come back down to earth with the "breakthrough" research that does not offer the average person a reasonable way to help prevent colorectal cancer.

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I just don't get it... the mainstream is still keeping aspirin on its little pedestal, despite the fact that we all know they are over-playing its benefits — if there are any at all.

The worst are the media reports on the latest and greatest findings of clinical trials involving aspirin... but if you really scrutinize the results there is always a catch or two.

Aspirin reduces colorectal cancer risk

A case in point (and there are many more) is a recent study that linked aspirin with a reduced risk of colorectal cancer.

First — the study only included patients with Lynch syndrome, a condition that sharply increases colorectal cancer risk. So while aspirin may have protected some Lynch syndrome patients from colorectal cancer, those results can't be extrapolated to the general population.

Second — subjects in the study received 600mg of aspirin daily. And that's a long LONG way from the 81mg low dose that's commonly recommended for heart benefits.

Those extra 519mg per day would dramatically increase risk of stomach bleeding, heart attack, and stroke — three known side effects caused by regular use of non-steroidal anti- inflammatory drugs (NSAIDs), which includes aspirin.

So let's come back down to earth with the "breakthrough" research that does not offer the average person a reasonable way to help prevent colorectal cancer.

For that, we can simply turn to a vitamin supplement...
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Out of the ordinary

Previously, I told you about the Journal of the American Medical Association (JAMA) meta-analysis of 13 studies, from Sweden's Karolinska Institute. Nine studies examined vitamin B6 intake, and four examined blood levels of PLP — the active form of B6. All the studies compared B6 status to cases of colorectal cancer.

Higher B6 intake and blood PLP levels were linked to lower colorectal cancer risk — and the higher the PLP levels, the stronger the link.

If lowering colorectal cancer risk was your only health concern,

A) You'd be very lucky, and

B) This JAMA summation of B6 research would be all the reason you'd need to make sure your daily intake was high.

This isn't the first time B6 appears as a colorectal cancer fighter. In fact, some of the previous studies I have told you about were very likely included in the JAMA analysis:

* A Harvard Medical School study showed that subjects with the highest B6 levels had a much lower risk of colorectal cancer compared to subjects with the lowest levels

* Tufts University research found that even a modest deficiency of key components in the B complex (including B6) increased colorectal cancer risk

* In a large study from Scotland's University of Edinburgh, high levels of B6 intake reduced colorectal cancer risk by more than 20 per cent

* Another Harvard trial found colorectal cancer risk significantly reduced among subjects who had the highest dietary intake of folate and B6

Super-duper vitamin

Just a few years ago, Dr John M. Ellis, put B6 on the map with a ground-breaking book, "Vitamin B6 Therapy: Nature's Versatile Healer". In it, Dr. Ellis explains that PLP is a coenzyme that activates many crucial enzyme systems. In fact, nearly 120 enzymes need B6 to function properly, and 19 out of your body's 20 amino acids require B6.

That's why it's no surprise that B6 also plays a key role in many other health issues, including immune function, hormone function, and cognitive function, as well as the prevention of heart disease, depression, kidney stones, breast cancer, and prostate cancer.

Now... let's see aspirin try to do all that with zero risk of side effects.

Uh... I don't think so.
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Sources:

"Aspirin Helps Reduce Colon Cancer, Study Shows" Brian Williams, NBC Nightly News, 10/27/11, msnbc.msn.com

"Vitamin B6 and Risk of Colorectal Cancer" Journal of the American Medical Association, Vol. 303, No. 11, 3/17/10, jama.ama-assn.org
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