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Cancer
New Cancer Breakthrough or Just Another Pharma Cash Cow?
Date: 07/12/11
Keywords: adverse side effects, Antioxidants, Brain Cancer, Breast Cancer, Cancer, Pancreatic Cancer, Ovarian Cancer
Like many drugs, the Bradford smart bomb's original source is Nature.
A flower called autumn crocus contains a toxic chemical called colchicine that kills human body tissues. But the Bradford team came up with the idea to synthesize an inactive form of colchicine that can be brought back to full toxicity when it senses the presence of an enzyme produced by solid tumours. This particular enzyme helps tumours to develop the tiny blood vessels that deliver oxygen and nutrients so that they can grow.
However, when the colchicine regains toxicity, it only attacks the enzyme and doesn't harm any other healthy cells.
Recently, the University of Bradford unveiled promising
cancer research at the annual British Science Festival, and
as you can imagine the media had a field day when they
reported on this latest research.
As expected, the media had a field day with headlines like "Smart bomb drug can wipe out cancer".
Coming from the same source
Like many drugs, the Bradford smart bomb's original source is Nature.
A flower called autumn crocus contains a toxic chemical called colchicine that kills human body tissues. But the Bradford team came up with the idea to synthesize an inactive form of colchicine that can be brought back to full toxicity when it senses the presence of an enzyme produced by solid tumours. This particular enzyme helps tumours to develop the tiny blood vessels that deliver oxygen and nutrients so that they can grow.
However, when the colchicine regains toxicity, it only attacks the enzyme and doesn't harm any other healthy cells.
So far, these results were only tested in animal studies. The Bradford team implanted mice with human cancer cells. Over the 60-day trial, the treatment shrunk tumours in every single mouse and completely erased tumours in half of them. The researchers also reported that there was no incidence of adverse side effects.
Lead researcher, Laurence Patterson, said that "Any treatment that is a poison that can be retained and is only active in the tumour is clearly very attractive."
In addition, the treatment also seeks out tumours that have spread through the body.
That really is impressive. However, there's one thing that bothers me about what Patterson said. He used the words 'poison' and 'attractive' in the same sentence... Somehow, that makes me feel uneasy, especially when we're talking about a cancer treatment that can potentially be given to millions of people.
Better, safer, cheaper and ready to use
Even if this drug really DOES prove to be effective, it won't hit the market for several years. Neither does it take away the fact that there's already a revolutionary anti- cancer 'smart bomb' at our disposal. But since it is not a drug, the mainstream still ignores it's powerful anti-cancer properties.
The real kicker is that it's not expensive, it's very safe since it's side effects are mild and umpteen studies support its cancer-fighting abilities.
Recently, National Institutes of Health (NIH) researchers implanted mice with three types of aggressive cancer cells: brain, pancreatic, and ovarian. In mice treated with intravenous ascorbic acid (IAA), cancer cell growth was cut in half compared to mice who weren't treated. And like the colchicine drug, IAA didn't harm healthy cells.
As I've mentioned before, the NIH study is by no means the first trial to show that mega doses of vitamin C kill cancer cells while leaving healthy cells intact. Plenty of other case studies have also shown the treatment to be effective against several common types of cancer.
The truth is, the Bradford study will get all the splashy headlines because the researchers are developing a patent drug. If human studies eventually show that it really is effective, the researchers, the university, and some lucky drug company stand to make billions of pounds from the patent for the treatment.
Since vitamin C cannot be patented, it will never be an insanely lucrative cash cow, so that's' why it will never make headlines.
Sad but true.
Sources:
"Smart bomb drug can wipe out cancer" Daily Express, 9/12/11, express.co.uk
"Chemotherapy breakthrough could dramatically reduce side- effects" Alok Jha, The Guardian, 9/12/11, guardian.co.uk
"California Catholics, Parental rights and Gardasil" Ed Silverman, Pharmalot, 7/1/11, pharmalot.com
Back to topAs expected, the media had a field day with headlines like "Smart bomb drug can wipe out cancer".
Coming from the same source
Like many drugs, the Bradford smart bomb's original source is Nature.
A flower called autumn crocus contains a toxic chemical called colchicine that kills human body tissues. But the Bradford team came up with the idea to synthesize an inactive form of colchicine that can be brought back to full toxicity when it senses the presence of an enzyme produced by solid tumours. This particular enzyme helps tumours to develop the tiny blood vessels that deliver oxygen and nutrients so that they can grow.
However, when the colchicine regains toxicity, it only attacks the enzyme and doesn't harm any other healthy cells.
So far, these results were only tested in animal studies. The Bradford team implanted mice with human cancer cells. Over the 60-day trial, the treatment shrunk tumours in every single mouse and completely erased tumours in half of them. The researchers also reported that there was no incidence of adverse side effects.
Lead researcher, Laurence Patterson, said that "Any treatment that is a poison that can be retained and is only active in the tumour is clearly very attractive."
In addition, the treatment also seeks out tumours that have spread through the body.
That really is impressive. However, there's one thing that bothers me about what Patterson said. He used the words 'poison' and 'attractive' in the same sentence... Somehow, that makes me feel uneasy, especially when we're talking about a cancer treatment that can potentially be given to millions of people.
Better, safer, cheaper and ready to use
Even if this drug really DOES prove to be effective, it won't hit the market for several years. Neither does it take away the fact that there's already a revolutionary anti- cancer 'smart bomb' at our disposal. But since it is not a drug, the mainstream still ignores it's powerful anti-cancer properties.
The real kicker is that it's not expensive, it's very safe since it's side effects are mild and umpteen studies support its cancer-fighting abilities.
Recently, National Institutes of Health (NIH) researchers implanted mice with three types of aggressive cancer cells: brain, pancreatic, and ovarian. In mice treated with intravenous ascorbic acid (IAA), cancer cell growth was cut in half compared to mice who weren't treated. And like the colchicine drug, IAA didn't harm healthy cells.
As I've mentioned before, the NIH study is by no means the first trial to show that mega doses of vitamin C kill cancer cells while leaving healthy cells intact. Plenty of other case studies have also shown the treatment to be effective against several common types of cancer.
The truth is, the Bradford study will get all the splashy headlines because the researchers are developing a patent drug. If human studies eventually show that it really is effective, the researchers, the university, and some lucky drug company stand to make billions of pounds from the patent for the treatment.
Since vitamin C cannot be patented, it will never be an insanely lucrative cash cow, so that's' why it will never make headlines.
Sad but true.
Sources:
"Smart bomb drug can wipe out cancer" Daily Express, 9/12/11, express.co.uk
"Chemotherapy breakthrough could dramatically reduce side- effects" Alok Jha, The Guardian, 9/12/11, guardian.co.uk
"California Catholics, Parental rights and Gardasil" Ed Silverman, Pharmalot, 7/1/11, pharmalot.com
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