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Digestive Problems

Could painkillers be triggering your dyspepsia?


Date: 22/01/08
 
Dyspepsia is a digestive malfunction that may prompt some or all of these symptoms: * Heartburn * Nausea * Gas * Bloating * Belching To make matters worse, the cause of dyspepsia is often unknown. But for the numerous people in the UK who cope with different forms of chronic arthritis, the cause of their dyspepsia may be no mystery - it's very likely prompted by frequent use of nonsteroidal anti-inflammatory drugs (NSAIDs).

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Dyspepsia is a digestive malfunction that may prompt some or all of these symptoms: 

* Heartburn
* Nausea
* Gas
* Bloating
* Belching

To make matters worse, the cause of dyspepsia is often unknown. But for the numerous people in the UK who cope with different forms of chronic arthritis, the cause of their dyspepsia may be no mystery - it's very likely prompted by frequent use of nonsteroidal anti-inflammatory drugs (NSAIDs).  
 
Dyspepsia and painkillers: Into the tunnel  
 
As noted in many e-Alerts, NSAIDs seriously stress the digestive system. According to commentary in the journal Clinical Cornerstone, long-term NSAIDs use is responsible for 100,000 hospitalizations per year due to upper gastrointestinal adverse events, and may contribute to an estimated 16,500 deaths per year. 
 
Researchers with Veterans Affairs (Greater Los Angeles Healthcare System) and UCLA, conducted a meta-analysis of studies that compared rates of dyspepsia among patients who treated arthritis with COX-2 inhibitors (such as Celebrex and Vioxx), and patients who took a combination of a NSAID and a proton pump inhibitor (PPI) drug (such as Nexium, Prevacid and Prilosec) to address stomach upset. 
 
Talk about a vicious cycle! PPIs suppress stomach acid, which may provide temporary heartburn relief, but also stresses digestion by reducing the acids that are necessary to digest food. In a past e-Alert I told you about a study that found PPI use sharply increased the risk of digestive inflammation and diarrhoea caused by a bacterium that's usually kept under control by - wait for it - stomach acid! 
 
The UCLA/VA team found that COX-2 users lowered dyspepsia risk by 12 per cent (compared to NSAIDs users) while patients who used the NSAIDs/PPI combo reduced dyspepsia risk by more than 65 per cent.  
 

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In a UCLA press release, the director of the study noted that NSAIDs combined with PPI drugs 'may prove to be the preferred treatment for arthritis patients at high risk for stomach problems.' 
 
If you'd like a perfect example of mainstream medicine's tunnel vision view of health care... there you go.  
 
Dyspepsia and painkillers: Go to town  
 
In a previous e-Alert, told you about two alternative treatments for dyspepsia:

1) capsaicin, a phytochemical that occurs naturally in red peppers, and
2) Potter's Acidosis, a herbal formula that HSI Panelist Dr Allan Spreen, recommends for indigestion, acid reflux, and other stomach problems. 
 
But arthritis patients may not need ANY treatments for dyspepsia if they avoid prescription medications and try one of these non-drug methods to address pain: 
 
GLUCOSAMINE & CHONDROITIN SULPHATE: In many e-Alerts we've examined these two essential components of cartilage that are naturally produced by the body, and in supplement form have been shown to slow and even reverse the degenerative effects of osteoarthritis. 
 
COD LIVER OIL: I've also told you about research that shows how cod liver oil may reverse the actions of the enzymes that break down cartilage. In fact, studies suggest that taking cod liver oil can even prevent the development of arthritis, while reducing symptoms in those already afflicted with the disease. 
 
NICOTINAMIDE: In a National Institutes of Health study, this anti-inflammatory nutrient (a derivative of niacin  - also known as vitamin B3) relieved arthritis pain by almost 30 per cent and improved range of motion and flexibility in joints. 
 
ACUPUNCTURE: Plus I've told you before about a study of 570 patients with knee osteoarthritis. Among the subjects who were treated with acupuncture, 40 per cent reported reduced pain. These subjects also had significant improvements in knee mobility and function.
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