Sytrinol: Breakthrough new heart-health formula helps lower your cholesterol level

Although cholesterol is usually thought of in a negative light, its not all bad. In fact, this complex fatty substance has many important functions in your body from keeping your cell membranes intact to making hormones, vitamin D, and bile acids which aid fat digestion.

Cholesterol can be made in your body by your cells and various organs, or supplied through foods of animal origin such as meat, dairy products and eggs. But while some cholesterol is vital for good health, too much of it in your blood can clog your arteries and increase your risk of heart disease and stroke.

The current Joint British Societies Guidelines state that a persons total cholesterol level should be 5.0mmol/l or below, and for those who have, or are at risk of, coronary heart disease, the target should be no higher than 4.0mmol/l. However, according to HEART UK, an organisation that offers information and advice on heart disease, the average total cholesterol level in the UK is 5.7.

Yet, as weve mentioned numerous times in HSI, keeping track of your cholesterol level isnt, on its own, a true gauge of your personal risk for heart disease. You also need to know your lipoprotein levels transport vehicles that carry fats and cholesterol between your intestines, liver and body cells.

There are two main types of lipoprotein: low-density lipoprotein (LDL) often referred to as bad cholesterol, and high-density lipoprotein (HDL) or good cholesterol. LDL carries cholesterol from your liver to your cells and increased levels are associated with atherosclerosis. HDL takes cholesterol away from your cells and back to your liver, where its either broken down or excreted. Thats why its known as good cholesterol. The greatest danger is if you have a high level of LDL coupled with a low level of HDL.

Healthy eating and regular physical exercise are the first steps in reducing your cholesterol. For many people, however, lifestyle changes may not be enough and lipid-lowering drugs called statins are often prescribed. Statins work by blocking the production of cholesterol, and although effective, have a number of side effects including headache, nausea, vomiting, constipation, diarrhoea and muscle pain. They have also been found to prevent the body producing co-enzyme Q10 an important heart nutrient.

Fortunately a breakthrough new product called Sytrinol has just been launched in the UK, which helps maintain the health of your cardiovascular system. It is made up of a blend of powerful antioxidants including polymethoxylated flavones (PMFs) and a range of palm (alpha, delta andgamma) tocotrienols. While each of these antioxidants has been found to have excellent heart-health benefits, scientists have discovered that they are even more powerful when combined. Studies have revealed that Sytrinol is able to significantly lower total cholesterol, LDL, and triglyceride (blood fat) levels. Better still, the formula has also been shown to increase HDL levels.

Active ingredients lower LDL levels and also help keep your arteries clear

Polymethoxylated flavones (PMFs), one of the main active ingredients in Sytrinol, are a group of compounds derived from the peels of citrus fruits. The two most common are tangeretin and nobiletin, extremely potent bioflavonoids. More than 25 years of documented research provides evidence that these particular bioflavonoids deliver heart health benefits.

Nobiletin and tangeretin help lower levels of LDL by preventing the creation of its building blocks: apolipoprotein B and triglycerides. Apolipoprotein B is considered the primary building block, making up almost 90 per cent of LDL cholesterol. Interestingly, triglycerides the main kind of fat in your body are one of the key contributors to the formation of apolipoprotein B.

Sytrinol is also made up of palm tocotrienols, which, like tocopherols, are members of the vitamin E family and are extracted from the fruit of the palm tree. Like vitamin E, palm tocotrienols control anti-inflammatory responses and degrade HMG-CoA reductase a key enzyme in your body used by your liver to produce cholesterol. Besides reducing cholesterol, palm tocotrienols have also been shown to inhibit arterial plaque formation and reduce blood platelet aggregation (clumping).

Palm tocotrienols are also powerful antioxidants, known to possess antioxidant potential far greater than that shown by vitamin E itself. In human studies, it was observed that alpha tocotrienols decreased the oxidation of LDL (Ref. 1). This action is important as raised LDL is a risk factor in cardiovascular disease, particularly when it has been oxidised by free radicals. The antioxidant properties of tocotrienols can minimise the damage caused by these compounds while protecting cell membranes. Scientists have found that tocotrienols accumulate at levels that are 25 to 95 times greater than vitamin E in tissue in the main artery (aorta) from the heart.

LDL:HDL ratio an important marker of heart health improved by almost 30 per cent

To date three main studies have been carried out to investigate Sytrinols effects on high cholesterol levels, the results of which are extremely promising.

The first study involved 60 participants with raised cholesterol levels. After taking 300mg of Sytrinol each day for four weeks, the researchers found that the treatment lowered total cholesterol by 25 per cent, the bad LDL cholesterol by 19 per cent, and triglycerides by 24 per cent (Ref. 2).

In the second, smaller study 10 subjects with elevated cholesterol levels benefited after four weeks of treatment with 300mg of Sytrinol per day. Sytrinol therapy lowered total cholesterol levels by 20 per cent, LDL cholesterol by 22 per cent, apolipoprotein B (a component of LDL) by 21 per cent, and triglycerides by 28 per cent. Additionally, subjects in this trial benefited from a significant 5 per cent increase in apolipoprotein A1 an important structural protein of the good HDL cholesterol (Ref. 3).

Researchers recently completed a third clinical trial, a 12-week placebo-controlled study involving 120 men and women with moderately elevated cholesterol levels. Compared to those in the placebo group, subjects taking Sytrinol had a decrease of 30 per cent in total cholesterol, 27 per cent in LDL cholesterol, and 34 per cent in triglycerides. In addition, HDL levels increased by 4 per cent, resulting in a significant 29 per cent improvement in the LDL:HDL ratio (Ref. 4).

What to take for best results

The recommended dosage for Sytrinol is one 150mg capsule taken twice a day, with or without food. Although Sytrinol works independent of diet and exercise, proper nutrition and regular physical activity are recommended as an all-round, holistic approach to developing good heart health.

References:

1. Quereshi A, Bradlow BA, Brace L, Manganello J, Elson CE, et al. Response of hypercholesterolemic subjects to administration of tocotrienols. Lipid 1995;30:1171-1177.

2-4 Talbott SM, Roza J, Guthrie N. Effect of citrus flavonoids and tocotrienols on serum cholesterol levels in hypercholesterolemic subjects. Series of studies submitted to Alternative Therapies in Health and Medicine, Boulder CO. www.source-1-global.com