Immunity: Boost Your Immunity and Lower Your Fatigue by Giving Your Liver the Support it Needs with CysteinePeP

For years researchers have attempted to harness the healing power of whey in a supplement. While a number of products have been developed, their high prices and large doses made them impractical. So researchers concentrated more and more on trying to isolate the active compound from whey the amino acid cysteine.

By isolating the cysteine, its now possible to get the benefits of whey without having to choke down a handful of pills.

Weve discovered a product called CysteinePeP that uses a unique extraction process to make it available in a smaller, less expensive dose than its forerunners. The process extracts the active cysteine peptides from the whey protein. CysteinePeP has been shown to enhance patients lives by providing energy, motivation, better sleep, and mental alertness.

Low levels of the bodys main antioxidant can lead to fatigue and other immune related conditions

One of the functions of the liver is to rid toxic materials from the body. Cysteine peptides help the liver function because they have an abundance of the amino acid cysteine. Your body uses cysteine along with two other plentiful amino acids, glutamine and glycine, to produce glutathione (GSH) in your liver cells. GSH is the bodys natural intracellular antioxidant and healing agent. It is a tripeptide, a molecule made up of three amino acids in its chemical structure cysteine, glutamine, and glycine.

The livers primary goal is to replenish your supply of GSH whether it has been depleted by an internal stressor (such as natural ageing) or an external one (such as alcohol consumption). GSH repletion leads to critical antioxidant protection, reversal of fatigue and superior immune function.

Its also a critical factor in protecting organisms against toxicity and disease.1

GSH plays a crucial role in preventing oxidative stress in cells and in trapping the free radicals that can damage DNA and RNA (ribonucleic acid). Unfortunately, as you age, your bodys GSH levels decrease. In fact, there is a direct correlation between the speed of ageing and the reduction of GSH concentrations in the cells.2, 3

But the problem with GSH is that you cant just take it orally to increase the levels in your system because it can be made only within the cells. However, you can raise the GSH levels
by supplementing your diet with the GSH precursor cysteine.

Thats why CysteinePeP is so powerful: It contains the cysteine your body needs most to produce GSH in your liver.

Cysteine peptides give your liver more immune-boosting power

Trials were conducted on rats to determine if cysteine peptides would be able to increase GSH synthesis in their livers. In two independent experiments, rats were fed a standard diet in which dietary protein was partially replaced by cysteine peptides.4 The results of both experiments showed that increasing the amounts of cysteine peptides in the diet increased the GSH concentration in rat livers.

Researchers found that the ingestion of 40 per cent of the diet as cysteine peptides resulted in an increase of GSH in rats of approximately 40 per cent. However, higher cysteine supplementation did not increase the livers use of GSH. The researchers believe that this shows that once GSH levels reach a certain point, GSH synthesis is decreased.5

In another rat study, researchers discovered that GSH binds to toxins in the liver in order to remove them. When this happens, GSH levels can be completely depleted even if there is already a high GSH level before it is challenged.

As the researchers explain, it seems that as soon as the toxin exhausts the defence capacity of the liver cells, damage will take place causing the demand for GSH to increase. The good news is that the capacity of the liver to convert cysteine into GSH also increases. Most severe liver damage starts with repetitive small injuries. Higher levels of GSH can address these smaller injuries before they become irreversible.

GSH aids in fighting immune diseases like CFS

Chronic fatigue syndrome (CFS) is a disease attributed to immune system dysfunction. Dr. Paul Cheney, M.D., Ph.D., a well-known CFS researcher in the US, has conducted studies leading him to conclude that GSH depletion is at the core of CFS and that GSH repletion is associated with recovery.

One of the factors involved in the development of CFS is a defect in the detoxification process. CFS sufferers, instead of removing toxins from the body, will slowly store away poisons in fatty tissue, muscles, organs, and the brain.

Because GSH is critical for detoxification, a deficiency in GSH will impair the bodys ability to get rid of toxins.

Cheney found a GSH deficiency in virtually all CFS patients he tested over the previous 10 years.6 When he used whey protein to correct the glutathione deficiency in his patients, he saw that their energy improved. Higher doses of whey protein produced even better results. Even though the study was small, it was enough to convince Dr. Cheney.

Long-term prevention

These studies indicate that cysteine peptides can help the liver in two ways. First, they protect the liver by offering long-term prevention. Second, they support recovery after acute injury (such as certain medical treatments, hepatitis, or regular alcohol ingestion). However, these applications will require further study.

So far, the only studies conducted have been on animals. However, HSI will keep our eyes open for future studies conducted with people. 

What to take for best results

CysteinePeP is a small 3.6g daily dose of the active compound required for GSH enhancement from whey protein. And with the lower dose comes a reasonable price.

The recommended dose of CysteinePeP is 3.6g of powder (200mg of cysteine). Simply mix it with water and drink. Based upon initial research, users should note that it will take four days to start experiencing benefits from enhanced glutathione. You can either take it all in the morning or at two separate times. However, if you take it in the evening, it could keep you awake at night.

1. Clinical Chimica Acta 2004; 349(1-2): 45-52
2. Exp Gerontol 2002; 37(12): 1333-1345
3. Adv Exp Med Biol 2003; 543:191-200
4. American Review of Respiratory Disease 1986; 134(2): 281-4
5. Strategies for increasing cellular GSH. Biothiols in Health and Disease. (New York: Marcel Dekker Inc., 1995) 165-188
6. Sieverling, Carol. Dr. Cheney on undenatured whey. CFIDS/FMS Support Group of DFW (http://virtualhometown.com/dfwcfids/medical/whey.html), 9/1/05